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To assess the prevalence of endometrial hyperplasia (EH), endometrial intraepithelial neoplasia (EIN) and endometrial carcinoma between obese and not obese women undergoing IVF techniques for primary or secondary infertility.
Endometrial cancer and pre-neoplastic diseases represent the most incident gynecologic malignant pathologies found in women.1 Although diagnosed in postmenopausal patients, it can be also found in younger patients, especially when associated with some risk factors. Those include weight gain and lifestyle habits, such as consumption of fatty foods that increase estrogen levels. The positive association be- tween infertility and EC is well established. Infertile women with irregular menstrual periods, oligomenorrhea, or chronic anovulation have a risk of developing
A prospective cohort study conducted at "Fertility Center, OB/GYN Unit, Department of Woman, Child and General and Specialized Surgery, University of Campania "Luigi Vanvitelli", Naples, Italy".
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Primary Infertility | Women with a diagnosed primary infertility undergoing hysteroscopy before IVF. |
| |
| Secondary Infertility | Women with a diagnosed secondary infertility undergoing hysteroscopy before IVF. |
| |
| Recurrent miscarriages | Women with recurrent miscarriages undergoing hysteroscopy before IVF. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| in-office hysteroscopy | Procedure | in-office hysteroscopy with miniaturized instruments |
|
| Measure | Description | Time Frame |
|---|---|---|
| Prevalence of endometrial hyperplasia | 12 months | |
| Hormonal levels | 12 months |
| Measure | Description | Time Frame |
|---|---|---|
| Operator's learning curve with cumulative summation test (questionnaire) | assess the learning curve (LC) using cumulative summation test for learning curve (LC-CUSUM). | 12 months |
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Inclusion Criteria:
Exclusion Criteria:
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Southern Italian women eager for children who are set for infertility work-up at a tertiary university hospital
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Woman, Child and General and Specialized Surgery, University of Campania "Luigi Vanvitelli" | Naples | 80138 | Italy |
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| ID | Term |
|---|---|
| D007247 | Infertility, Female |
| D004714 | Endometrial Hyperplasia |
| ID | Term |
|---|---|
| D005831 | Genital Diseases, Female |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
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| D000091662 | Genital Diseases |
| D007246 | Infertility |
| D014591 | Uterine Diseases |