Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Assessing the volume of the liver before surgery, predicting the volume of liver remaining after surgery, detecting primary or secondary lesions in the liver parenchyma are common applications that require optimal detection of liver contours, and therefore liver segmentation.
Several manual and laborious, semi-automatic and even automatic techniques exist.
However, severe pathology deforming the contours of the liver (multi-metastatic livers...), the hepatic environment of similar density to the liver or lesions, the CT examination technique are all variables that make it difficult to detect the contours. Current techniques, even automatic ones, are limited in this type of case (not rare) and most often require readjustments that make automatisation lose its value.
All these criteria of segmentation difficulties are gathered in the livers of hepatorenal polycystosis, which therefore constitute an adapted study model for the development of an automatic segmentation tool.
To obtain an automatic segmentation of any lesional liver, by exceeding the criteria of difficulty considered, investigators have developed a convolutional neural network (artificial intelligence - deep learning) useful for clinical practice.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Neuronal network Training group | The following radiological variables, related to each CT examinations, will be collected for each patient:
|
| |
| Neuronal network Validation group | The following radiological variables, related to each CT examinations, will be collected for each patient:
|
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Anonymized CT examinations | Other | The anonymized CT examinations will be reviewed in Lyon, in the imaging department of Edouard Herriot Hospital, by an expert radiologist and an intern from the Lyon hospitals. |
| Measure | Description | Time Frame |
|---|---|---|
| Test of automatic segmentation by the convolutional neural network on these group and collection of data set | Development of an automatic segmentation tool for highly dysmorphic polycystic livers as a prerequisite for segmentation of any type of multi-lesional livers that are difficult to segment, in order to facilitate lesion detection and volume measurement in clinical practice. Randomisation of the patient into two data groups, one for training the other for Validating the convolutional neural network (artificial intelligence)
| At 4 months after randomization |
Not provided
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Patients with hepato-renal polycystosis, with or without surgery
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Bénédicte CAYOT | Contact | 472110400 | +33 | benedicte.cayot@chu-lyon.fr |
| Pierre-Jean VALETTE, MD, Prof. | Contact | 472117544 | +33 | pierre-jean.valette@chu-lyon.fr |
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Service de radiologie - Pavillon B - Cellule Recherche imagerie, Hôpital Edouard Herriot (HCL) | Recruiting | Lyon | 69437 | France |
Not provided
| ID | Term |
|---|---|
| C536330 | Polycystic liver disease |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Training (1) | Other | An initial training phase of the artificial intelligence network will be carried out : - Segmentation of the livers of a first part of the CT examination, by an intern of the Lyon hospitals |
|
| Training (2) | Other | An initial training phase of the artificial intelligence network will be carried out : - Use of computer data to drive the artificial intelligence network. |
|
| Validation (1) | Other | A validation phase of the artificial intelligence tool will be carried out with segmentation of the livers of the second part of the CT examinations : - Carried out by an intern at the Lyon hospitals |
|
| Validation (2) | Other | A validation phase of the artificial intelligence tool will be carried out with segmentation of the livers of the second part of the CT examinations : - Carried out by the neural network |
|