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This study aims to provide an estimate of the incidence of paraneoplastic neurological syndromes and autoimmune encephalitides in France between the years 2016 and 2018. The study will describe the incidence of antibody subtypes and regional variations.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Paraneoplastic neurological syndromes patients | Patients tested for Paraneoplastic neurological syndromes (PNS) and Autoimmune Encephalitis (AE) with a lumbar puncture, with detection of an antibody or negative, but with PNS clinically diagnosed. |
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| Measure | Description | Time Frame |
|---|---|---|
| Incidence and prevalence of diagnosed Paraneoplastic Neurological Syndromes (PNS) and Autoimmune Encephalitis (AE) between 2016 and 2018. | Comparison between general population of the French counties and the cohort of PNS to calculate incidence and prevalence. | 3 years |
| Measure | Description | Time Frame |
|---|---|---|
| Location (city) of diagnosis | Name of city where the diagnosis of Paraneoplastic Neurological Syndromes (PNS) or Autoimmune Encephalitis (AE) was made. | 1 hour |
| French general population of each counties |
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Inclusion Criteria:
- Clinical diagnosis of Paraneoplastic Neurological Syndrome (PNS) or Autoimmune Encephalitis (AE) made by the referring physician to the national center for PNS and AE in Lyon between 2016 and 2018
Exclusion Criteria:
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Patients diagnosed with a paraneoplastic neurological syndrome or autoimmune encephalitis in France and referred to the national center in Lyon between 2016 and 2018.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Géraldine Picard | Contact | 4 72 35 58 42 | 33 | geraldine.picard@chu-lyon.fr |
| Jérôme Honnorat | Contact | 4 72 35 78 06 | 33 | jerome.honnorat@chu-lyon.fr |
| Name | Affiliation | Role |
|---|---|---|
| Jérôme Honnorat | center for paraneoplastic neurological syndromes and autoimmune encephalitis | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Centre de référence des syndromes neurologiques paranéoplasiques et encéphalites auto-immunes | Lyon | 69003 | France |
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| ID | Term |
|---|---|
| D020274 | Autoimmune Diseases of the Nervous System |
| ID | Term |
|---|---|
| D009422 | Nervous System Diseases |
| D001327 | Autoimmune Diseases |
| D007154 | Immune System Diseases |
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Person years for each region
| 3 years |