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Background:Hyperglycemia and hypoglycemia both cause detrimental side effects for pediatric patients. Prolonged fasting time, age dependent physiological diffences and individual differences of patients make complicated the perioperative fluid therapy. Isotonic electrolyte solutions without glucose or with lower glucose concentrations recommended for intraoperative period in pediatric patients.
Objective: The aim of this prospective study is to evaluate the different glucose concentrations(without dextrose, 1 % dextrose+LR, 2 % dextrose+LR) in perioperative infusion solutions according to preoperative blood glucose level to maintain normoglycemia in pediatric patients.
Method: The consecutive 250 eligible pediatric patients aged between 6 months- 12 years with ASA risk score of I-II undergoing surgery lasting less than four hours were enrolled the study in six months period. Patient demographics, procedure, preoperative fasting time, preoperative and postoperative glucose levels were documented. Lactate ringer (LR) solution with % 2 glucose was infused to the patients with preoperative blood glucose level lower than 60 mg/dL, LR solution with % 1 glucose was used for the patients with preoperative blood glucose level between 60-90 mg/dL, LR solution without glucose was used for the patients with preoperative blood glucose level higher than 90 mg/dL.
Lactate ringer (LR) solution with % 2 glucose was infused to the patients with preoperative blood glucose level lower than 60 mg/dL, LR solution with % 1 glucose was used for the patients with preoperative blood glucose level between 60-90 mg/dL, LR solution without glucose was used for the patients with preoperative blood glucose level higher than 90 mg/dL
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| non glucose infusion group | Active Comparator | Drug: LR infusion LR solution without glucose; the patients with preoperative blood glucose level higher than 90 mg/dL. |
|
| Drug:1% Dextrose infusion group | Active Comparator | Drug:LR+ 1% Dextrose infusion LR solution with % 1 glucose: the patients with preoperative blood glucose level between 60-90 mg/dL, |
|
| 2% Dextrose infusion group | Active Comparator | Drug:LR+ 2 % Dextrose infusion Lactate ringer (LR) solution with % 2 glucose; the patients with preoperative blood glucose level lower than 60 mg/dL, |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Drug: dextrose containing infusion | Procedure | Drug: infusing dextrose containing or non glucose fluid according to blood glucose level |
|
| Measure | Description | Time Frame |
|---|---|---|
| glucose level | blood glucose level measurement with finger stick monitoring | perioperative period |
| Measure | Description | Time Frame |
|---|---|---|
| hyperglysemia or hypoglysemia ratio | blood glucose level measurement with finger stick monitoring | perioperative |
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İnclusion criteria;
Exclusion Criteria:
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3 different type of fluid
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