Evaluation of the Contribution of Regular Cognitive Exercises to Treatment in Patients With Alzheimer's Disease

Evaluation of the Contribution of Regular Cognitive Exercises to Treatment in Patients With Alzheimer's Disease Receiving Donepezil, Memantine or Donepezil/Memantine Combination Therapy: Open-Labeled, Randomized, Phase IV, Superiority Study

In this study, it is aimed to compare the effects of cognitive exercises applied on long-term internet environment to the cognitive level of patients who received donepezil, memantine or donepezil / memantin combination therapy.

Inclusion Criteria:

• Patients between 55-90 years old who were diagnosed with Alzheimer's Dementia and had no history of cerebrovascular disease during the last 6 months,
• Patients without other neurodegenerative diseases and secondary dementia diagnoses,
• Patients with MOCA score of between 13-18,
• Patients with at least primary school graduation,
• Patients who have had no CNS disease including trauma in the last year,
• Patients without a diagnosis of psychiatric disease,
• Patients with a tablet or PC with an internet connection,
• Patients agreeing to perform BEYNEX daily activity at least 5 times per week,
• Patients signing informed consent form.

Exclusion Criteria:

• Patients who have hypersensitivity to study working drugs,
• Psychotic patients,
• Disabled patients with orthopedic dominant extremity,
• Patients with ICU follow-up due to trauma in the last 6 months,
• Patients with severe visual impairment or eye surgery,
• Patients who refuse to sign the informed consent form.