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The aim of this study is to determine the influence of acute resistance exercises on anatomical and biological changes in the quadriceps muscle and tendons of the knee
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| One acute resistance load exercise | Active Comparator | One hundred volunteers will participate in one acute resistance load exercises to their quadriceps |
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| Three acute resistance load exercises | Active Comparator | One hundred volunteers will participate in three acute resistance load exercises to their quadriceps |
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| Control Group | Active Comparator | One hundred volunteers will participate in study as a control group |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Acute resistant load exercises | Other | Leg bench and leg press acute resistant load exercises Leg-bench and leg-press acute resistant load exercises |
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| Measure | Description | Time Frame |
|---|---|---|
| Genetic Changes in Knee Muscle and Tendon | Comparison of results of genetic testing both before and after interventions between the 3 groups | One year |
| Ultrasound Changes in Knee Muscle and Tendon | Comparison of results of pre- and post ultrasound changes after interventions between the 3 groups | One year |
| Biopsy Changes in Knee Muscle and Tendon | Comparison of changes in biopsies taken before and after interventions between the 3 groups | One year |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Eias Kassem, MD | Contact | 972-50-6246882 | eiask@hy.health.gov.il |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hillel Yaffe Medical Center | Hadera | 38100 | Israel |
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| Background Questionnaire | Behavioral | Background questionnaire will be filled out by participants |
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| Pain Questionnaire | Other | Pain questionnaire regarding pain in the knee during previous 3 months |
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| DNA and RNA test | Genetic | DNA and RNA tests will be sent to a genetic laboratory for analysis |
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| Ultrasound | Diagnostic Test | Ultrasound of the knee joint and the quadriceps muscle and the pica tendon |
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| Percutaneous Needle Core Biopsy | Diagnostic Test | Core Biopsy will be taken from the quadriceps femoris muscle |
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| ID | Term |
|---|---|
| D004247 | DNA |
| D014463 | Ultrasonography |
| ID | Term |
|---|---|
| D009696 | Nucleic Acids |
| D009706 | Nucleic Acids, Nucleotides, and Nucleosides |
| D003952 | Diagnostic Imaging |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
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