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Aim of the study is assessment the prevalence of the low ankle-brachial index (ABI) defined less than or equal 0.9 in patients with acute cerebral ischemic event (stroke or transient ischemic attack) and determinate the correlation between ABI and internal carotid artery stenosis (ICAS) in the acute cerebral ischemic patients.
The low ABI is a strong marker of generalized atherosclerosis. LEAD is a strong independent predictor for stroke.
Aim of the study is assessment the prevalence of the low ankle-brachial index (ABI) defined less than or equal 0.9 in patients with acute cerebral ischemic event (stroke or transient ischemic attack) and determinate the correlation between ABI and internal carotid artery stenosis (ICAS) in the acute cerebral ischemic patients.
The ABI is a non-invasive tool useful for the diagnosis of LEAD. The low ABI is a strong marker of generalized atherosclerosis. LEAD is a strong independent predictor for stroke. Significant ICAS is prevalent among patients having LEAD. Acute ischemic stroke due to significant ICAS has poor prognosis.
Patients with LEAD may be a suitable subgroup for screening for ICAS using duplex scanning.
Estimating the relationship between cerebral ischemic event and the ABI value could help better guide preventive and risk reduction strategies.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| STROKE GROUP | 150 patients admitted to Stroke Unit with a diagnosis of acute ischemic stroke (IS) or transient ischemic attack (TIA) |
| |
| CONTROL GROUP | 50 individuals admitted to hospital without diagnosis of acute cerebrovascular disease; with diagnosis of dizziness, epilepsy, sclerosis multiplex. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Duplex scanning of carotid arteries | Device | Measurement of carotid arteries |
|
| Measure | Description | Time Frame |
|---|---|---|
| ABI | Prevalence of a low ankle-brachial index (ABI) in patients with acute cerebral ischemic event | 7 days |
| Measure | Description | Time Frame |
|---|---|---|
| ABI/ICAS | Correlation between ABI and internal carotid artery stenosis (ICAS) in the acute cerebral ischemic patients. | 7 days |
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Inclusion Criteria:
Exclusion Criteria:
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Patients attending to hospital settings diagnosed with acute ischemic event (stroke or TIA) and control group individuals undergo computed tomography (CT) or magnetic resonance imaging (MRI) of the brain, lipid profile, had stroke risk factors assessed.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Paweł Sokal, Ph.D. | Contact | 600954415 | 48 | pawel.sokal@cm.umk.pl |
| Name | Affiliation | Role |
|---|---|---|
| Paweł Sokal, Ph.D. | Jan Biziel University Hospital Collegium Medicum Nicolaus Copernicus University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Neurosurgery and Neurology University Hospital nr 2 Collegium Medicum Nicolaus Copernicus University | Recruiting | Bydgoszcz | 85-168 | Poland |
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| ID | Term |
|---|---|
| D000083242 | Ischemic Stroke |
| ID | Term |
|---|---|
| D020521 | Stroke |
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
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| ABI measurement | Device | ankle brachial index (ABI) assessment |
|
| D009422 |
| Nervous System Diseases |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |