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| ID | Type | Description | Link |
|---|---|---|---|
| 2019/14MAR/124 | Other Identifier | CEHF |
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| Name | Class |
|---|---|
| BioMérieux | INDUSTRY |
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The objective of this study is to measure how the use of Film-Array Pneumonia (FA-PNEU) on respiratory samples of adult patients suspected of acute care pneumonia in the intensive care unit of Saint-Luc University Hospital can accelerate / improve the initiation of the optimal antibiotic treatment.
The main objective of this trial is to confirm/attest/prove the following statement:
The use of the FilmArray Pneumonia panel on respiratory samples of critically ill suspected with pneumonia, enables a faster microbiological pneumonia diagnosis and an improved therapeutic management of the patient.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| control | No Intervention | Respiratory samples are treated according to routine laboratory testing : culture, immuno assays | |
| Intervention | Experimental | Respiratory samples are treated according to routine laboratory testing : culture, immuno assays AND molecular testing (FilmArray PNEU) of the endotracheal aspirate sample 24 hours a day. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| FilmArray Pneumonia | Diagnostic Test | FilmArray Pneumonia testing of tracheal sample |
|
| Measure | Description | Time Frame |
|---|---|---|
| Turn Around Time Treatment | Turn Around Time administration of optimal antimicrobial treatment | 48 hours from arrival of the respiratory sample at the laboratory |
| Measure | Description | Time Frame |
|---|---|---|
| Performances FilmArray Pneumonia | Microbiological performances FA-PNEU test versus routine microbiology testing | 1 week from arrival of the respiratory sample at the laboratory |
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Inclusion Criteria:
Suspicion will be based on symptoms, clinical, biological and radiological criteria.
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Alexia VERROKEN | Cliniques universitaires St-Luc | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Cliniques Universitaires Saint-Luc | Brussels | 1200 | Belgium |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 33395094 | Derived | Kerneis S, Visseaux B, Armand-Lefevre L, Timsit JF. Molecular diagnostic methods for pneumonia: how can they be applied in practice? Curr Opin Infect Dis. 2021 Apr 1;34(2):118-125. doi: 10.1097/QCO.0000000000000713. |
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| ID | Term |
|---|---|
| D011014 | Pneumonia |
| ID | Term |
|---|---|
| D012141 | Respiratory Tract Infections |
| D007239 | Infections |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
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Open Randomized study, consecutive 2 weeks-period for observation group and study group
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