FiO2 and Outcomes After Cardiac Surgery With Cardiopulmonary Bypass

Effect of Intraoperative Oxygen Tension on Patient Outcomes After Cardiac Surgery With Cardiopulmonary Bypass: a Pilot Study

Conventionally, a relatively high level of fraction of inspired oxygen (FiO2) has been used for secure a margin of safety in patients undergoing cardiac surgery using cardiopulmonary bypass (CPB). Since the potential adverse effects of hyperoxemia (via reactive oxygen species, vasocontriction, perfusion heterogeneity, myocardiac injury, etc.), various studies on this topic has been performed. However, the results are conflicting and inconsistent, and the consensus about whether the use of additional oxygen supply in cardiac surgery using CPB has not been reached among practitioners yet.

Inclusion Criteria:

• All patients scheduled for cardiac surgery using cardiopulmonary bypass

Exclusion Criteria:

• Planned implementation of deep hypothermic circulatory arrest
• Preoperative respiratory support with the fraction of inspired oxygen of 0.5 and more.