Combination With Treg Levels and CMR to Assess the Severity and Prognosis of Reperfusion Injury After PPCI in STEMI Patients

Combination With Regulatory T Cell Levels and Cardiac Magnetic Resonance Imaging (CMR) to Assess the Severity and Prognosis of Reperfusion Injury After Primary PCI in STEMI Patients (TregCMRRS)

This study aims to determine whether combination with regulatory T cell (Treg) levels and cardiac magnetic resonance imaging (CMR) are predictive of the severity of reperfusion injury following myocardial infarction and the prognosis in STEMI patients receiving primary percutaneous coronary intervention (PPCI).

Inclusion Criteria:

• Confirmed STEMI diagnosis
• Undergoing primary percutaneous coronary intervention (presenting <12 hours after symptom onset)
• Patients were able to complete cardiac magnetic resonance imaging (CMR) and speckle tracking imaging echocardiogram (STE) examinations
• Patients agreed and provided informed consent

Exclusion Criteria:

• Previous myocardial infarction or revascularization (PCI or CABG)
• Congestive heart failure with LVEF<40%
• Atrial fibrillation
• Renal insufficiency (GFR < 30 ml/min/1.73m^2)
• Acute infectious diseases within nearly 3 months
• Rheumatic immune system diseases
• Malignant tumors
• Claustrophobia
• Contraindicated to CMR
• Patients do not agree to be included in the study