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World-wide, patients waiting for organ transplantation exceed the number of organs available. Many European countries have a uDCDD program which contribute to 10-15% of the donor pool. In Canada, this type of program does not exist. The purpose of this study is to report how many deceased person fulfill the criteria for uncontrolled DCDD in a Canadian medical center.
While transplantation has become the definitive treatment for many people suffering end-stage organ failure, demand exceeds supply. For many years, donation after neurological death represented the principal source of organs for transplantation. In the last decade, prevention measures, improvements in neurocritical care, and decompressive craniectomy have led to a significant decrease in the number of non-directed donors (NDDs). In such situations, alternative sources for organ donation must be identified. Cardiac-arrest patients could provide a solution to this organ shortage. Patients who have experienced unexpected in or out of hospital cardiopulmonary arrest could become organ donors. Organ donation following uncontrolled cardiocirculatory death is currently practiced in many European countries. However, in Canada, it's not yet authorized. Yet, each deceased could save up to four lives. The purpose of this study is to determine the organ potential for a cohort of patient who had died from a cardiopulmonary arrest at the CHUS in 2015 and assess the effect of the implementation of a uDCD program on the number of additional donors.
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| Measure | Description | Time Frame |
|---|---|---|
| Potential contribution of a uDCDD program on the number of additional donors. | Defined as (must meet all criteria):
| 1 year |
| Measure | Description | Time Frame |
|---|---|---|
| Effect of the implementation of a uDCDD program on the number of additional organs suitable for transplantation. | Effect of the implementation of a uDCDD program on the number of additional organs suitable for transplantation. | 1 year |
| Number of tissus donors |
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Inclusion Criteria:
Exclusion Criteria:
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This study will be conducted in one organ-donation center in Quebec that is a teaching hospital and referral center for interventional cardiology. It serves a mixed urban and rural population of 350,000.
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| Name | Affiliation | Role |
|---|---|---|
| Frédérick D'Aragon, Dr/Pr | Université de Sherbrooke | Principal Investigator |
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Number of tissus donors |
| 1 year |
| Potential obstacles and solutions related to the implementation of a uDCDD program in Canada. | Potential obstacles and solutions related to the implementation of a uDCDD program in Canada. | 1 year |
| Areas of future research. | Areas of future research. | 1 year |