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| Name | Class |
|---|---|
| Asan Medical Center | OTHER |
| Samsung Medical Center | OTHER |
| Pusan National University Hospital | OTHER |
| Severance Hospital |
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The incidence and prevalence of pulmonary disease due to Non-tuberculous mycobacteria (NTM) is increasing worldwide, and this trend has been confirmed in Korea. Treatment of NTM pulmonary disease is difficult and usually requires more than two years of long-term treatment, and the antibiotic regimens used in treatment vary. Therefore, it is difficult to track the natural history of patients with NTM pulmonary disease, to evaluate the treatment outcome, and to understand the effect of specific medicines on the outcome. Establishing a prospective registry of patients with NTM pulmonary disease is expected to accurately evaluate the progress, treatment modality, and treatment outcome of NTM pulmonary disease.
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| Measure | Description | Time Frame |
|---|---|---|
| Treatment success rate | Analysis of treatment success rate according to species of NTM lung disease patients in Korea | Through study completion, at 1 year after treatment start at enrollment |
| Measure | Description | Time Frame |
|---|---|---|
| Comparison of the efficacy among different regimens for the treatment of certain species of NTM | Comparison of the outcomes measured by culture conversion among different regimens for the treatment of certain species of NTM | Through study completion, at 1 year after treatment start at enrollment |
| Number of participants with changing culture results during treatment |
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Inclusion Criteria:
Exclusion Criteria
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Patients with NTM lung disease initiating treatment at each hospital participating in the study
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41723437 | Derived | Yang S, Park Y, Kwak N, Hwang H, Jeon D, Jhun BW, Jo KW, Kim HJ, Kim JY, Kim YR, Kwon YS, Lee JH, Mok J, Shim TS, Sohn H, Whang J, Kim J, Park N, Lee GI, Yim JJ, Kang YA. Association between nutritional status and clinical characteristics in nontuberculous mycobacterial pulmonary disease: preliminary results from the NTM-KOREA cohort. Respir Res. 2026 Feb 21;27(1):116. doi: 10.1186/s12931-026-03579-5. | |
| 38563246 |
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| ID | Term |
|---|---|
| D008171 | Lung Diseases |
| ID | Term |
|---|---|
| D012140 | Respiratory Tract Diseases |
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| OTHER |
| Pusan National University Yangsan Hospital | OTHER |
| Chonnam National University Hospital | OTHER |
| Korean Institute of Tuberculosis | OTHER |
| International Tuberculosis Research Center | OTHER |
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Number of participants with changing culture results during treatment |
| Through study completion, at 1 year after treatment start at enrollment |
| Number of participants with treatment-related adverse events | Number of participants with treatment-related adverse events specifically described in the protocol | Through study completion, at 1 year after treatment start at enrollment |
| Derived |
| Kwak N, Henkle E, Hwang H, Jeon D, Jhun BW, Jo KW, Kang YA, Kim HJ, Kim JY, Kim YR, Kwon YS, Lee JH, Mok J, Park Y, Shim TS, Sohn H, Whang J, Yim JJ. Improvement in Health-Related Quality of Life Following Antibiotic Treatment in Nontuberculous Mycobacterial Pulmonary Disease: Initial Analysis of the NTM-KOREA Cohort. Clin Infect Dis. 2024 Jun 14;78(6):1690-1697. doi: 10.1093/cid/ciae131. |