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In this study, the prevalence of metabolic syndrome in psoriatic and psoriatic arthritis patients as well as the parameters of metabolic syndrome will be examined. At the same time, the levels of omentin and visfatin adipokines associated with metabolic syndrome and obesity will be measured by measuring the disease severity (by PASI psoriasis, clinical activity score for psoriatic arthritis). The patients who accepted to participate in the study , who were admitted to the dermatology outpatient clinic were included in the study. For the blood tests required after the examination, 2 tubes of blood will be taken for the measurement of omentin and visfatin. 80 psoriasis, 40 psoriatic arthritis and 60 healthy volunteers were planned to be studied. AHA / NHLBI, 2005 (revised ATP III criteria) criterion for the diagnosis of metabolic syndrome will be used. Omentin and visfatin levels are compared with the severity of the disease for psoriasis and psoriatic arthritis, and it will be examined whether it is proinflammatory or antiinflammatory.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| psoriasis vulgaris, | Other | patients who have only psoriasis vulgaris |
|
| psoriatic arthritis | Other | patients who have psoriatic arthritis |
|
| healthy control | Other | healthy people |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| omentin, visfatin | Diagnostic Test | diagnostic blood test |
|
| Measure | Description | Time Frame |
|---|---|---|
| omentin | Omentin (omentin 1-2) is a specific protein that consists of amino acids released from vascular vessels | 6 months |
| visfatin | Visfatin is an insulin-like protein that binds to insulin receptors produced mostly from visceral fatty tissue. | 6 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Istanbul Medeniyet University, Department of dermatology | Istanbul | 34722 | Turkey (Türkiye) | |||
| Istanbul Medeniyet University |
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| ID | Term |
|---|---|
| D015535 | Arthritis, Psoriatic |
| D024821 | Metabolic Syndrome |
| ID | Term |
|---|---|
| D025242 | Spondylarthropathies |
| D025241 | Spondylarthritis |
| D013166 | Spondylitis |
| D013122 | Spinal Diseases |
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| Istanbul |
| 34722 |
| Turkey (Türkiye) |
| D001847 |
| Bone Diseases |
| D009140 | Musculoskeletal Diseases |
| D001168 | Arthritis |
| D007592 | Joint Diseases |
| D011565 | Psoriasis |
| D017444 | Skin Diseases, Papulosquamous |
| D012871 | Skin Diseases |
| D017437 | Skin and Connective Tissue Diseases |
| D007333 | Insulin Resistance |
| D006946 | Hyperinsulinism |
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |