Effect of Self Assembling Peptide on White Spot Lesion

Evaluation of the Re-mineralizing Effect of Biomimetic Self-Assembling Peptides in Post Orthodontic White Spot Lesions Compared to Fluoride-Based Delivery Systems

During re-mineralization of white spot lesion, Will biomimetic self-assembling peptides improve the re-mineralizating effect of the post orthodontic white spot lesion compared to fluoride-based delivery systems?

Conservative dentistry no longer prefers the "drill and fill" concept and advocates reversal of lesions via remineralization. . Remineralization is the process of restoring minerals - again, in the form of mineral ions - to the hydroxyapatite latticework structure. It is three-dimensional, and the lost ions must be replaced with ions having the exact same shape, size and the same electrical charge as those lost from the lattice.

Fluoride and self-assembling peptides have been used as adjuncts to enhance remineralization.

Inclusion Criteria:

• Patients with post orthodontic white spot lesion.
• Patients with good oral hygiene.
• Patients with good general health.
• Cooperative patients.
• Subjects who signed the informed consent.

Exclusion Criteria:

• Patients with tetracycline pigmentation and dental fluorosis.
• Enamel cavitation.
• Disable patient.
• patient with any systemic disease or severe medical complications.