Preclinical Cardiomyopathy and Autonomic Function in Type 1 Diabetes

Preclinical Cardiomyopathy in Type 1 Diabetes: Correlation With Autonomic Dysfunction

Type 1 diabetes mellitus is a chronic autoimmune disease, associated with an increased risk of cardiovascular diseases. The development of cardiomyopathy in type 1 diabetes, independent of hypertension and coronary heart disease, is still controversial. A possible mechanism for diabetic cardiomyopathy is autonomic dysfunction. This study aims to evaluate cardiac function and structure, and to relate them with autonomic dysfunction in type 1 diabetes.

Inclusion Criteria:

• type 1 diabetes mellitus

Exclusion Criteria:

• hypertension
• coronary artery disease
• heart valve disease
• ventricular dysfunction
• radiotherapy or chemotherapy
• alcoholism
• limited acoustic window