Muco-ciliary Cleansing of Lungs in COPD With and Without a Salt Particle Inhaler

Muco-ciliary Cleansing of Lungs in COPD With and Without a Salt Particle Inhaler

Cross-over trial of the effect of a salt particle inhaler on pulmonary muco-ciliary cleansing in COPD patients as measured by lung scintigraphy.

Stable COPD patients will be examined twice with minimum two, maximum 14 days interval. In randomized order the patients will inhale from a salt particle inhaler with (active) or without (placebo) content.

Inclusion Criteria:

• COPD grade 1, 2 and 3 in stable condition (less than 10% change of FEV1 ratio between investigation visits

Exclusion Criteria:

• Pregnant or lactating women
• Patients exposed to radionuclear isotopes within one month
• Patients under antibiotic treatment
• Patients with known hyper reactive airways