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The post operative routine after Oculoplastic Surgery includes usage of cold compressions for symptomatic relief and decreasing of the edema and local hematomas in the first few days after the surgery. Khat (Catha edulis) is a plant that is used mainly for chewing and has a known stimulating effect, some patients report major improvement after including these leaves in the compressions they use after surgery. Khat contains the chemical ingredients Cathine and Cathinone, which are amphetamine-like alkaloids and probably the main contributors for its active effects. Our main goal is to use compressions that include the Khat leaves and check their effect on reducing the edema and hematomas after oculoplastic surgery.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients after Oculoplastic surgery | Experimental | Each participant will use one compression with Khat leaves and another standard compression and will decide on which eye to use which compression. The compressions will be used for 10 minutes per every waking hour in the first 2 days post-op. The patient will take pictures of both his eyes in days 1,3 and 7 post operative days. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Khat leaves | Biological | One of the two compressions (one per each eye) the patient will use will contain the Khat leaves. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Edema | Improvement in edema in the Khat compression in comparison to standard compression by clinical evaluation. | 7 days post op |
| Hematoma | Improvement in hematomas in the Khat compression in comparison to standard by compression by clinical evaluation. | 7 days post op |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Guy J Ben Simon, MD | Contact | 97235302874 | guybensimon@gmail.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Sheba_Medical_Center | Ramat Gan | 52621 | Israel |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 27429228 | Background | Malhotra R, Ziahosseini K, Poitelea C, Litwin A, Sagili S. Effect of Manuka Honey on Eyelid Wound Healing: A Randomized Controlled Trial. Ophthalmic Plast Reconstr Surg. 2017 Jul/Aug;33(4):268-272. doi: 10.1097/IOP.0000000000000743. |
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| ID | Term |
|---|---|
| D006406 | Hematoma |
| D000072836 | Surgical Wound |
| D004487 | Edema |
| ID | Term |
|---|---|
| D006470 | Hemorrhage |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D014947 | Wounds and Injuries |
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Each participant is his own control
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| D012816 | Signs and Symptoms |