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This study proposes: to evaluate 1) whether the combination of virtual reality (VR) and active tDCS provides better rumination attenuation than the combination of VR and tDCS placebo 2) the acceptability and experiential experience of combining these two well known medical devices.
Inclusion visit:
Visit 1 and 2 (or end of study visit) :
Before first ruminations induction :
Then Procedure for inducing ruminations using a pre-recorded voice listened to in an audio headset alternating statements promoting a positive, neutral and negative introspection and self-judgment attitude (the latter are heard at the end to initiate the rumination process) over 8 minutes
Then
Then immersion in a relaxing virtual environment for 20 minutes with active or sham placebo.
• Cutaneous conductance measurement and eye-tracking during immersion
At the end of immersion :
Then again procedure for inducing ruminations .
At the end of ruminations induction :
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| VR + active brain stimulation | Experimental | Exposure to a virtual reality world with active transcranial electric stimulation |
|
| VR + sham brain stimulation | Sham Comparator | Exposure to a virtual reality world with sham transcranial electric stimulation |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| VR + active brain stimulation | Device | Active Brain stimulation (tDCS) is applied during exposition to virtual reality (20 minutes) |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change in anxious ruminations after anodal tDCS and virtual reality | Change in anxious ruminations after anodal tDCS and virtual reality will be evaluated to compare the effects of tDCS associated with virtual reality versus virtual reality alone (+ tDCS placebo) to reduce ruminations. Evaluate with Brief State Ruminative Inventory (BSRI). It is a scale with 8 items. Each item is VAS with a score ranging between 0 and 100. The total score is sum of each item score (Total /800) | within 1 week |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University Hospital | Nantes | France |
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| ID | Term |
|---|---|
| D000079562 | Rumination Syndrome |
| ID | Term |
|---|---|
| D005767 | Gastrointestinal Diseases |
| D004066 | Digestive System Diseases |
| D001068 | Feeding and Eating Disorders |
| D001523 | Mental Disorders |
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| VR +sham brain stimulation | Device | Sham Brain stimulation (tDCS) is applied during exposition to virtual reality (20 minutes) |
|