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Enrollment not sufficient for data analysis.
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Retrospective review of images used to target the STN during DBS procedure and ability of the Surgical Information Sciences ("SIS") system to visualize the STN location.
The purpose of this study is to collect retrospective data to demonstrate the ability of the SIS system to visualize the MRI-defined STN in patients with Parkinson's Disease (PD) who have undergone deep brain stimulation (DBS) procedure targeting the STN.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| SIS System | Device | Software technology for visualization of anatomical structures in the brain |
| Measure | Description | Time Frame |
|---|---|---|
| Percent of STN Visualization Success | Measure the proportion of images successfully processed for visualization of the STN over total number of image sets | Day 1 |
| Incidence of DBS Lead Location in Proximity to STN | Determine incidence in which the location of the DBS lead is in or outside the STN | Day 1 |
| Measure | Description | Time Frame |
|---|---|---|
| Rate of Correlation of Predicted Outcome to Monopolar Review Outcome | Rate of blinded predicted outcome compared to monopolar review outcomes | 1 Month |
| Rate of Correlation of DBS Lead Location to Long Term Outcomes |
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Key Inclusion Criteria:
Key Exclusion Criteria:
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Subjects who have completed bilateral or unilateral high frequency stimulation of the subthalamic nucleus (STN-HFS) for idiopathic PD and have pre and post operative MR and CT imaging, programming data, Unified Parkinson's Disease Rating Scale Part III (UPDRS-III) scores and a 3-6 month follow-up evaluation
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| Name | Affiliation | Role |
|---|---|---|
| Noam Harel, PhD | Surgical Information Sciences | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| UPMC | Pittsburgh | Pennsylvania | 15213 | United States |
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| ID | Term |
|---|---|
| D010300 | Parkinson Disease |
| ID | Term |
|---|---|
| D020734 | Parkinsonian Disorders |
| D001480 | Basal Ganglia Diseases |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
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Rate of agreement between SIS-defined model of STN and actual DBS lead location and clinical motor outcomes
| 3-6 months |
| D009422 | Nervous System Diseases |
| D009069 | Movement Disorders |
| D000080874 | Synucleinopathies |
| D019636 | Neurodegenerative Diseases |