Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| Koç University | OTHER |
Not provided
Not provided
Not provided
Not provided
The effect of auricular stimulation on the locomotion capability in patients with Parkinson's Disease was investigated.
Effect of the auricular stimulation as a supplementary and alternative usage to Levodopa was investigated in this study. Clinical data were collected through motion capture system while the participants performed the clinical task asked by the investigators.
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Sole Medication | No Intervention | Monitoring under current prescribed medication | |
| Combined stimulation & medication | Active Comparator | Concurrent usage of stimulation with the prescribed medication |
|
| Sole Stimulation | Active Comparator | Alternating usage of stimulation to the prescribed medication |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Percutaneous electrical nerve stimulation | Device | Stimulation and medication at the same instant |
|
| Measure | Description | Time Frame |
|---|---|---|
| Stride length [m] | Measurement through motion capture system | Time Frame: Baseline |
| Stride length [m] | Measurement through motion capture system | Time Frame: 20 minutes after stimulation is initiated |
| Stride length [m] | Measurement through motion capture system | Time Frame: 40 minutes after stimulation is initiated |
| Stride length [m] | Measurement through motion capture system | Time Frame: 60 minutes after stimulation is initiated |
| Stride velocity [m/s] | Measurement through motion capture system | Time Frame: Baseline |
| Stride velocity [m/s] | Measurement through motion capture system | Time Frame: 20 minutes after stimulation is initiated |
| Stride velocity [m/s] | Measurement through motion capture system | Time Frame: 40 minutes after stimulation is initiated |
| Stride velocity [m/s] | Measurement through motion capture system | Time Frame: 60 minutes after stimulation is initiated |
Not provided
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Yusuf O Cakmak, MD, PhD | Otago University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Koc University Hospital | Istanbul | Turkey (Türkiye) |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 33117256 | Derived | Cakmak YO, Ozsoy B, Ertan S, Cakmak OO, Kiziltan G, Yapici-Eser H, Ozyaprak E, Olcer S, Urey H, Gursoy-Ozdemir Y. Intrinsic Auricular Muscle Zone Stimulation Improves Walking Parameters of Parkinson's Patients Faster Than Levodopa in the Motion Capture Analysis: A Pilot Study. Front Neurol. 2020 Oct 7;11:546123. doi: 10.3389/fneur.2020.546123. eCollection 2020. |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D010300 | Parkinson Disease |
| ID | Term |
|---|---|
| D020734 | Parkinsonian Disorders |
| D001480 | Basal Ganglia Diseases |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
Not provided
Not provided
| ID | Term |
|---|---|
| D004561 | Transcutaneous Electric Nerve Stimulation |
| D004304 | Dosage Forms |
| ID | Term |
|---|---|
| D004599 | Electric Stimulation Therapy |
| D013812 | Therapeutics |
| D026741 | Physical Therapy Modalities |
| D012046 | Rehabilitation |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Percutaneous electrical nerve stimulation | Device | Stimulation is given without administering medication |
|
|
| Turning Velocity [deg/s] | Measurement through motion capture system | Time Frame: Baseline |
| Turning Velocity [deg/s] | Measurement through motion capture system | Time Frame: 20 minutes after stimulation is initiated |
| Turning Velocity [deg/s] | Measurement through motion capture system | Time Frame: 40 minutes after stimulation is initiated |
| Turning Velocity [deg/s] | Measurement through motion capture system | Time Frame: 60 minutes after stimulation is initiated |
| Double Support Percentage during walking [%] | Measurement through motion capture system | Time Frame: Baseline, 20 minutes, 40 minutes, 60 minutes |
| Double Support Percentage during walking [%] | Measurement through motion capture system | Time Frame: 20 minutes after stimulation is initiated |
| Double Support Percentage during walking [%] | Measurement through motion capture system | Time Frame: 40 minutes after stimulation is initiated |
| Double Support Percentage during walking [%] | Measurement through motion capture system | Time Frame: 60 minutes after stimulation is initiated |
| Swing Phase Percentage during walking [%] | Measurement through motion capture system | Time Frame: Baseline |
| Swing Phase Percentage during walking [%] | Measurement through motion capture system | Time Frame: 20 minutes after stimulation is initiated |
| Swing Phase Percentage during walking [%] | Measurement through motion capture system | Time Frame: 40 minutes after stimulation is initiated |
| Swing Phase Percentage during walking [%] | Measurement through motion capture system | Time Frame: 60 minutes after stimulation is initiated |
| Stance Phase Percentage during walking [%] | Measurement through motion capture system | Time Frame: Baseline, 20 minutes, 40 minutes, 60 minutes |
| Stance Phase Percentage during walking [%] | Measurement through motion capture system | Time Frame: 20 minutes after stimulation is initiated |
| Stance Phase Percentage during walking [%] | Measurement through motion capture system | Time Frame: 40 minutes after stimulation is initiated |
| Stance Phase Percentage during walking [%] | Measurement through motion capture system | Time Frame: 60 minutes after stimulation is initiated |
| D009422 | Nervous System Diseases |
| D009069 | Movement Disorders |
| D000080874 | Synucleinopathies |
| D019636 | Neurodegenerative Diseases |
| D000698 |
| Analgesia |
| D000760 | Anesthesia and Analgesia |
| D004364 | Pharmaceutical Preparations |
| D013678 | Technology, Pharmaceutical |
| D008919 | Investigative Techniques |