The purpose of the study is to look at the effect a dietary supplement called CEAG [Curcuminoids, EPA (Omega-3), Astaxanthin and Gamma Linolenic Acid (GLA)] has on inflammation and endothelial (inner layer of the blood vessels) function and whether it causes a lowering of blood pressure.The endothelium plays in an important role in blood pressure.

This clinical trial is to assess the efficacy of Curcuminoids, EPA (Omega-3), Astaxanthin and GLA for improving inflammation and endothelial reactivity over a four week intervention period in individuals with metabolic syndrome. The study also examines the effect of Curcuminoids, EPA (Omega-3), Astaxanthin and GLA administration on other markers of cardiovascular function and cardiovascular disease risk including Total, LDL and HDL-Cholesterol, Triglycerides, and a multitude of inflammatory markers.

Inclusion Criteria:

• age 18-75 years
• BP 121-140/81-90 mm Hg on average
• Body Mass Index (BMI) 18-40.

Exclusion Criteria:

• free of chronic diseases including cancer or rheumatologic disorders
• weight in excess of 350 pounds
• bleeding disorder
• history of myocardial infarction or all types of revascularization procedures, second or third degree heart block with or without a pacemaker
• angina pectoris of any type
• concurrent potentially life-threatening arrhythmia or symptomatic arrhythmia clinically significant valvular heart disease
• history of malignancy of any organ system, treated or untreated, within the past 5 years whether or not there is evidence of local recurrence or metastases, (with the exception of localized basal cell carcinoma of the skin)
• serum creatinine > 2.0 mg/dl
• concurrent enrollment in another placebo-controlled trial.