Use of Biodesign® Otologic Graft in Tympanoplasty

Use of Biodesign® Otologic Graft in Tympanoplasty: A Prospective, Randomized Trial

This is a prospective, randomized trial to evaluate tympanoplasty outcomes using Biodesign SIS graft compared to autologous temporalis fascia, the most commonly used graft for repair of tympanic membrane.

Patients 18 years or older will undergo primary tympanoplasty without mastoidectomy. The patients will be randomized into groups receiving Biodesign versus autograft temporalis fascia for repair.

Inclusion Criteria:

• Patients undergoing primary tympanoplasty without mastoidectomy.

Exclusion Criteria:

• Patients with a known biologic sensitivity or a cultural objection to use of porcine materials.