Anomalies of Nocturnal Gaz Exchanges in Patients With Down Syndrome

Anomalies of Nocturnal Gaz Exchanges in Patients With Down Syndrome Aged From 4 to 16 Years

Recently, retrospective studies have shown that Down Syndrome children have a higher CO2 (carbone dioxide) sleep pressure than the general pediatric population. This increase does not seem to be always related to sleep apnea. The Investigators wish to confirm these results prospectively. The investigators hypothesize that this alveolar hypoventilation may be due to ventilatory control disorders caused by dysautonomia, but also to a decrease in the strength of the respiratory muscles within the framework of the global muscular hypotonia described in children with Down syndrome. .

47 Down syndrome patients age from 4 to 16 will be included. They will perform a medical visit at J0, then a measurement of gaz nocturnal exchanges at home within 1 month

Inclusion Criteria:

• Down syndrome patient without mosaicism
• Age 4 to 16 years
• Predominant French language in the living environment

Exclusion Criteria:

• OAS diagnostic focused on an earlier polysomnography
• Methylphenidate treatment started before inclusion