Lactobacillus Rhamnosus and PCOS Treatment

The Effect of Lactobacillus Rhamnosus Supplementation on Body Mass, Hyperandrogenism and Insulin Resistance in Overweight and Obese Polycystic Ovary Syndrome Women - Randomized Nutritional Study

The effect of Lactobacillus rhamnosus supplementation on body weight, hyperandrogenism and insulin resistance in overweight and obesity women with Polycystic Ovary Syndrome will be analysed.

Inclusion criteria:

• patients diagnosed with PCOS,
• BMI> 28 kg/m2 (overweight or obesity),
• patients not participating in other similar research programs at the same time,
• no previous operations on ovaries such as: laparoscopy, ovarian cautery etc.,
• written agreement to take part in the research.

Exlusion criteria:

• the use of antibiotics or probiotics within 6 months before the start of the experiment,
• the use of pharmacological agents or hormones that may affect the course of the menstrual cycle or metabolic rate within 3 months,
• the use of medicament that may affect on carbohydrate metabolism within 4 weeks,
• failure to comply with dietary recommendations established during the nutritional intervention,
• the use of weight loss supplements during the study,
• clinical diagnosis of digestive disease (for example: irritable bowel syndrome, ulcerative colitis, Crohn's disease, celiac disease),
• pregnancy and breast feeding.