Tomographic and Histologic Assessment on the Influence of the Use of a Collagen Membrane to Protect the Antrostomy After Maxillary Sinus Floor Augmentation.

Cone Beam Computed Tomography and Histomorphometric Assessments on the Influence a Collagen Membrane Placed on the Antrostomy After Maxillary Sinus Floor Augmentation. A Randomized Clinical Trial.

the aim of the present study was to evaluate the dimensional variation and osseointegration of mini-implants at augmented sinus with the antrostomy left unprotected or protected with a collagen membrane.

The Schneiderian mucosa will be elevated and the created space will be filled with a natural bovine bone grafting material (Cerabone® 1-2 mm, Botiss Biomaterials GmbH). In ten patients randomly selected (control sties), a native collagen membrane made of porcine dermis (Collprotect®, Botiss Biomaterials GmbH) will be placed on the antrostomy. In another ten patients of the test group, the antrostomy will be left without the membrane. The flaps will be sutured and anti-inflammatory drugs and antibiotics will be administrated to the patients. The sutures will be removed after 7 days. After 6 months of healing, two mini-implants with different surface will be installed and retrieved after further 3 months for histomorphometric evaluations.

CBCTs will be taken for all patients before surgery (T0), after 1 week from sinus floor augmentation (T1) and after 9 months of healing (T2) and evaluation of dimensional variations over time of soft and hard tissues will be performed.

Inclusion Criteria:

• Presence of an edentulous atrophic zone in the posterior segment of the maxilla
• Height of the sinus floor ≤4 mm.
• Desiring a prosthetic restoration of the zone using a fix prosthesis supported by implants
• ≥ 21 years of age
• Good general health
• No contraindication for oral surgical procedures
• Not being pregnant.

Exclusion Criteria:The patients will be excluded if they present:

• A systemic disordered.
• Had a chemotherapic or radiotherapeutic treatment.
• Are smokers >10 cigarettes per day
• Have an acute or a chronic sinusitis.
• Had a previous bone augmentation procedures in the zone of interest.