Is Oxidative Stress in Semen Reduced by Lifestyle Intervention

Is Oxidative Stress in Semen Reduced by Lifestyle Intervention

In this study we aim to investigate whether a 3-month life-style intervention would reduce oxidative stress (OS) in semen in men of infertile couples attending IVF-treatment. Men with a DFI above 15% (SCSA method) are recruited for intervention with a 3-month follow-up.

It is hypothesized that men who also have a OS above 1.34 using a novel OS diagnostic method (MiOXSYS) respond better to antioxidant treatment with a change in OS and DFI. The primary outcome is the change in OS following the intervention. Secondary outcomes are morphological semen parameters and DNA fragmentation index.

Inclusion Criteria:

• DFI>15
• Attending IVF treatment for unknown or male factor infertility.

Exclusion Criteria:

• Genetic diseases
• Azospermia