100 women with severe preeclanpsia received Magnesium sulfate 6 grams intravenous over 20 minutes as a loading dose. Resistance index [RI], pulsatility index [PI] and systolic/diastolic [S/D] ratio of the umbilical artery, uterine aryery and fetal middle cerebral artery before and repeated 20 minutes after intravenous administration of 6 grams of magnesium sulphate (loading dose) over 20 minutes . fetal breathing movements and fetal gross movements are counted within 20 minutes, before and after intravenous administration of 6 grams of magnesium sulphate (loading dose) over 20 minutes

100 women with severe preeclanpsia received Magnesium sulfate 6 grams intravenous over 20 minutes as a loading dose. Resistance index [RI], pulsatility index [PI] and systolic/diastolic [S/D] ratio of the umbilical artery, uterine aryery and fetal middle cerebral artery before and repeated 20 minutes after intravenous administration of 6 grams of magnesium sulphate (loading dose) over 20 minutes . fetal breathing movements and fetal gross movements are counted within 20 minutes, before and after intravenous administration of 6 grams of magnesium sulphate (loading dose) over 20 minutes

Inclusion Criteria:

• Singleton pregnancy.

• Primigravida or Multigravida.

• Pregnant females ≥ 37 weeks of gestation.

• Diagnosed as severe preeclampsia by the following criteria:

  • Sustained systolic blood pressure of ≥160 mmHg or a sustained diastolic blood pressure of ≥ 110 mmHg.
  • Proteinuria measured as +1 or more by dipstick or 24 hours urine collection with proteinuria ≥ 0.3 grams.
  • Oliguria or creatinine > 1.1 mg%.
  • Laboratory findings characteristic of HELLP syndrome.
  • Symptoms suggestive of severe preeclampsia ; severe headache, blurring of vision, epigastric pain.

Exclusion Criteria:

• Multifetal pregnancy.
• History of epilepsy.
• Patients with diabetes.
• Patients with renal disease.
• Fetuses with congenital anomalies.
• Patients receiving anticoagulants e.g. heparin (unfractionated or low molecular weight).
• Patients with severe IUGR.
• Patients with accidental hemorrhage.