The Effect of Vitamin D on Fertility

Effects of Vitamin D Supplements on Pregnancy Outcomes in Embriyo Transfer Cycles

Objective: To examine the effect of vitamin D supplements on the pregnancy and clinical pregnancy rate in embryo transfer cycles.

Design: Experimental study with a pre- and post-test. Setting: In Vitro Fertilization Center Patients: Its sample consisted of 118 women, 58 in the experimental group and 60 in the control group.

Intervention(s): At the beginning of the infertility treatment, the experimental group took vitamin D supplements, and the control group did not. Vitamin D supplementation for infertile women includes regulation of a diet rich in vitamin D, educational and motivational interviews about insolation, and taking vitamin D orally.

Main Outcome Measure(s): 25(OH)D and beta HCG levels

Inclusion Criteria:

• 18-45 years old
• literate in Turkish
• voluntary participation
• primarily infertile
• had undergone controlled ovarian hyperstimulation and had a fresh ET
• vitamin D levels lower than 30ng/mL before infertility treatment

Exclusion Criteria:

• patients with uncorrected congenital or acquired uterine anomalies
• bone, parathyroid gland, kidney and liver disorders
• use of anticonvulsants/antacid drugs
• taking dietary supplements contain vitamin D
• secondary infertility