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Cardiac involvements in autoimmune diseases (AD) is common but underestimated and an early detection remains a clinical challenge for lacking of efficient imaging methods. The objective of the study was to investigate LV myocardial abnormalities in AD patients by multimodal cardiac imaging, including speckle-tracking echocardiology (STE), cardiac magnetic resonance imaging (CMRI) and positron emission tomography (PET).
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| Measure | Description | Time Frame |
|---|---|---|
| Change in deformational parameters in echocardiography during follow-up period | global longitudinal strain (%), circumferential strain (%) and radial strain (%) measured by STE in autoimmune diseases | 6 months - 1 year - 2 years |
| Progression of myocardial fibrosis and edema during follow-up period | Late Gadolinium Enhanced, T1 mapping and T2 mapping tested by CMRI | 1 year - 2 years |
| Change in myocardial perfusion during follow-up period | SUVmax examined by PET | 1 year - 2 years |
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Inclusion Criteria:
Exclusion Criteria:
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Patient is diagnosed with autoimmune diseases, including systemic lupus erythematosus (SLE), vasculitis, dermatomyositis, sjogren's syndrome, scleroderma, rheumatoid arthritis and IgG4 associated disease.
Patient is capable of complying with study procedures.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Wei Chen, MD | Contact | 13911363358 | chen_wei0201@aliyun.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Peking Union Medical College Hostipal | Recruiting | Beijing | Beijing Municipality | 100010 | China |
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| ID | Term |
|---|---|
| D001327 | Autoimmune Diseases |
| ID | Term |
|---|---|
| D007154 | Immune System Diseases |
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