Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| Community Health Centre Ljubljana | OTHER |
| Slovenian Research Agency | OTHER |
| Valens Int. d.o.o., Slovenija | INDUSTRY |
Not provided
Not provided
Not provided
Not provided
The effect of content of barley beta-glucans in bread on postprandial blood sugar will be measured with open-label crossover study. Study will be conducted in Slovenia on 10-12 adult subjects who will test three barley beta-glucan containing bread formulations (food) in comparison with a reference white bread. Objective of the study is to investigate the influence of the content of barley beta-glucan in bread on glycaemic index (incremental area under the curve (IAUC) for the blood glucose response curve for barley beta-glucan containing breads in comparison to reference white bread.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| REFERENCE: white bread - BGL0 [RP] | Active Comparator | Participants consume a meal of bread BGL0 standardised to contain 25 g of available carbohydrates. Sample consumed together with 300 mL of water in up to 15 minutes. |
|
| TEST: b-glucan enriched bread - BGL2 [IP1] | Experimental | Participants consume a meal of bread BGL2 standardised to contain 25 g of available carbohydrates. Sample consumed together with 300 mL of water in up to 15 minutes. |
|
| TEST: b-glucan enriched bread - BGL3 [IP2] | Experimental | Participants consume a meal of bread BGL3 standardised to contain 25 g of available carbohydrates. Sample consumed together with 300 mL of water in up to 15 minutes. |
|
| TEST: b-glucan enriched bread - BGL4 [IP3] | Experimental | Participants consume a meal of bread BGL4 standardised to contain 25 g of available carbohydrates. Sample consumed together with 300 mL of water in up to 15 minutes. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| REFERENCE: white bread - BGL0 [RP] | Other | Determination of glycemic response after consumption of BGL0. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change in glycaemic response (capillary blood glucose) | Change in incremental area under the curve (IAUC) the blood glucose response curve for barley beta-glucan containing breads (investigational products; IP1-3), in comparison to white bread (reference product; RP) | 2 hours |
Not provided
| Measure | Description | Time Frame |
|---|---|---|
| Glucose level as measured with continuous glucose monitor (CGM) | up to 3 hours |
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Igor Pravst, PhD | Institut za nutricionistiko | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Nutrition Institite | Ljubljana | 1000 | Slovenia |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| TEST: b-glucan enriched bread - BGL2 [IP1] | Other | Determination of glycemic response after consumption of BGL0. |
|
| TEST: b-glucan enriched bread - BGL3 [IP2] | Other | Determination of glycemic response after consumption of BGL0. |
|
| TEST: b-glucan enriched bread - BGL4 [IP3] | Other | Determination of glycemic response after consumption of BGL0. |
|
| ID | Term |
|---|---|
| D051550 | I-kappa B Kinase |
| ID | Term |
|---|---|
| D017346 | Protein Serine-Threonine Kinases |
| D011494 | Protein Kinases |
| D017853 | Phosphotransferases (Alcohol Group Acceptor) |
| D010770 | Phosphotransferases |
| D014166 | Transferases |
| D004798 | Enzymes |
| D045762 | Enzymes and Coenzymes |
| D047908 | Intracellular Signaling Peptides and Proteins |
| D011506 | Proteins |
| D000602 | Amino Acids, Peptides, and Proteins |
Not provided
Not provided