To evaluate that perioperative regular usage of propacetamol to reduce post cesarean section uterine contraction pain and opioid consumption

The most common method of pain control after cesarean section is intravenous patient-control analgesia (IVPCA) with morphine. Multimodal analgesia could improve the quality of perioperative pain control and reduceside effects of opioids. Previous researches marked that perioperative pain after cesarean section includes somatic wound pain and visceral uterine contraction pain.

According to Academy of Breastfeeding Medicine, propacetamol is a safe pain-killer for an expectant mother and almost free from breast milk after intravenous injection. This study is a prospective double-blind randomized-controlled trial to evaluate that propacetamol could reduce visceral uterine contraction pain after cesarean section. Post cesarean section women will divide into three groups:

1. pain control with IVPCA for 2 days
2. pain control with IVPCA and propacetamol 1g every 6 hours for 2 days
3. pain control with IVPCA and propacetamol 2g every 6 hours for 2 days

Inclusion Criteria:

• Pregnancy more than 36 weeks which is expected to receive Caesarean section
• Post Caesarean section woman, age greater than or equal to 20 years old
• ASA physical status class 1 or 2

Exclusion Criteria:

• ASA physical status class 3 or above
• Less than 20 years old
• Past caesarean section for longitudinal wounds
• Undergone major abdominal surgery
• Chronic pain
• Allergic to morphine or Propacetamol
• Liver dysfunction
• Treatment with anticoagulant
• Emergency operation

Post Caesarean section woman