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Uveitis or inflammation of the uveal tract results from a heterogeneous collection of disorders of varying etiologies and pathogenic mechanisms. Uveitis is relatively frequent in industrial countries with an estimation of 115 cases for 100 000 persons and is associated with a blindness risk of 10%. Causes of uveitis can be related to different etiologies (infectious, inflammatory or general inflammatory diseases). Therapeutic care is based on ophthalmologic and systemic diagnosis and treatment strategy depends on the severity of inflammation.
The main objective of the Lyon uveitis study is to analyze the uveitis ophthalmologic etiology and diagnostic and therapeutic care of the patients. This study is proposed to all patients diagnosed for uveitis and referred to the Department of Internal Medicine of the Croix Rousse hospital, Lyon, france for etiologic diagnosis or treatment.
Analysis of i) patients' characteristics, ii) the relevance of complementary exams to determine the uveitis etiology, iii) treatment used.
This study will allow a better characterization of the disease on diagnosis practices and therapeutic care.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| No specific intervention. Collection of clinical data | Other |
| Measure | Description | Time Frame |
|---|---|---|
| Clinical evolution (persistence or resolution) evaluated by gradation of SEN | Persistence of disease is characterized by persistence of intraocular inflammation evaluated by gradation of SEN. (reference: A Standardization Grading System for Scleritis . Ophthalmology 2011 Apr;118(4):768-71). SEN score ranges from 0 to 5 (resolution = score 0 and persistence = score >0) | At one year after diagnosis |
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Inclusion Criteria:
Exclusion Criteria:
-
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This study is proposed to all patients diagnosed for uveitis and referred to the Department of Internal Medicine of the Croix-Rousse hospital, Lyon, France for the first visit corresponding to etiologic diagnosis or treatment.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Pascal Sève, MD, PhD | Contact | +33-4 26 73 26 27 | pascal.seve@chu-lyon.fr |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Internal Medicine, Croix-Rousse Hospital, Hospices Civils de Lyon | Recruiting | Lyon | 69004 | France |
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| ID | Term |
|---|---|
| D014605 | Uveitis |
| ID | Term |
|---|---|
| D014603 | Uveal Diseases |
| D005128 | Eye Diseases |
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