Researchers are investigating improved methods of targeting deep brain stimulators for treatment of essential tremor relying on brain connectivity measures derived from MRI.

Inclusion Criteria:

• Diagnosis of refractory essential tremor scheduled for unilateral thalamic deep brain stimulator placement
• Age ≥ 18 years

Exclusion Criteria:

• Prior deep brain stimulator, stereotactic radiosurgery, or focused ultrasound procedure for treatment of tremor
• Presence of concomitant movement disorder (e.g. Parkinson's disease, dystonia, etc.)
• Known pre-existing structural brain abnormality (e.g, infarction, tumor, prior brain surgery, etc.)
• Contraindication to 3 Tesla brain MRI (e.g. incompatible implanted device)
• Pregnant