Next-Generation Pre-Operative Targeting for Thalamic DBS in the Treatment of Tremor

Transform the Practice: Next-Generation Pre-Operative Targeting for Thalamic DBS in the Treatment of Tremor

Researchers are investigating improved methods of targeting deep brain stimulators for treatment of essential tremor relying on brain connectivity measures derived from MRI.

Inclusion Criteria:

• Diagnosis of refractory essential tremor scheduled for unilateral thalamic deep brain stimulator placement
• Age ≥ 18 years

Exclusion Criteria:

• Prior deep brain stimulator, stereotactic radiosurgery, or focused ultrasound procedure for treatment of tremor
• Presence of concomitant movement disorder (e.g. Parkinson's disease, dystonia, etc.)
• Known pre-existing structural brain abnormality (e.g, infarction, tumor, prior brain surgery, etc.)
• Contraindication to 3 Tesla brain MRI (e.g. incompatible implanted device)
• Pregnant