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Pilot study of a wearable gas and sweat skin sensor
The objective of this study is exploratory and deploys two wearable sweat and gas sensors which detect the composition of sweat proteins and volatile gases emitted from the skin in healthy subjects and patients with atopic dermatitis.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Healthy Adults | Healthy adults with no prior diagnosis of atopic dermatitis |
| |
| Atopic Dermatitis | Adults with prior diagnosis of Atopic Dermatitis from board certified dermatologist |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Gas sensor | Device | The gas sensor is an airtight gas capsule attached with a floating solid phase microextraction (SPME) tube. SPME uses a fiber coated with a nontoxic liquid (polymer), and a nontoxic solid (sorbent). The fiber coating extracts the compounds from the gas being released from the skin. Only the glass sample is in contact with the skin. |
| Measure | Description | Time Frame |
|---|---|---|
| Evaluation of gas exudates | Evaluation of protein contents from gas exudates from the skin | 20 minutes |
| Evaluation of sweat proteins | Evaluation of protein contents from sweat from the skin | 20 minutes |
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Inclusion Criteria:
Exclusion Criteria:
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Healthy adults and adults with prior diagnosis of atopic dermatitis from made by board certified dermatologist
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| Name | Affiliation | Role |
|---|---|---|
| Shuai Xu, MD | Northwestern University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Northwestern University | Chicago | Illinois | 60610-5402 | United States |
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| ID | Term |
|---|---|
| D003876 | Dermatitis, Atopic |
| ID | Term |
|---|---|
| D012873 | Skin Diseases, Genetic |
| D030342 | Genetic Diseases, Inborn |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |
| D003872 | Dermatitis |
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| Sweat Sensor | Device | The sweat sensor is a soft, flexible device that rests on the skin and collects secreted sweat through capillary action. The device is held in place by medical-grade acrylic adhesive film. |
|
| D012871 | Skin Diseases |
| D017437 | Skin and Connective Tissue Diseases |
| D017443 | Skin Diseases, Eczematous |
| D006969 | Hypersensitivity, Immediate |
| D006967 | Hypersensitivity |
| D007154 | Immune System Diseases |