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To investigate the effect of added sugar to bake beans on glycemic and insulinemic response.
There will be a total of 7 test session. Each session will last for 3 hours. At each test session, volunteers will be served with 7 test meals and blood will be collected. After an overnight fast, subjects will visit the research center. Two fasting capillary blood samples will be collected via fingerpick. Following the fasting samples, volunteers will consume the test meals. Further blood samples will be collected at 15, 30, 45, 60, 90, 120, 150, 180 minutes after the ingestion of test meal. These samples will be used to analyses for whole capillary blood glucose. At every 30 minute interval, samples will be collected for analysis of capillary plasma insulin.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Glucose Reference 1 | Other | Glucose solution containing 30 g of glucose |
|
| Glucose Reference 2 | Other | Glucose solution 2 containing 30 g of glucose |
|
| Glucose Reference 3 | Other | Glucose solution 3 containing 30 g of glucose |
|
| Sucrose | Experimental | Sucrose solution containing 30 g of sucrose |
|
| Regular Bake beans in tomato sauce | Experimental | Bake bean in tomato sauce with high levels of sucrose (37%) |
|
| Bake beans in tomato sauce, reduced sugar | Experimental | Bake bean in tomato sauce with medium levels of sucrose (29.9%) |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Glucose Reference 1 | Other | 30 g of glucose dissolved in 250 ml of water |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Glucose [ | Whole capillary blood glucose will be measure using Hemocue analyser | Up to 180 minutes |
| Measure | Description | Time Frame |
|---|---|---|
| Insulin | Capillary plasma will be measure using Cobas analyser | Up to 180 minutes |
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Inclusion Criteria:
Exclusion Criteria:
Healthy Male Volunteers
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Clinical Nutrition Research Centre | Singapore | 117599 | Singapore |
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Crossover randomized controlled Trials
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|
| Bake beans in tomato sauce, low GI | Experimental | Bake bean in tomato sauce with low levels of sucrose (18.5%) |
|
| Glucose Reference 2 |
| Other |
30 g of glucose dissolved in 250 ml of water |
|
| Glucose reference 3 | Other | 30 g of glucose dissolved in 250 ml of water |
|
| Sucrose | Other | 30 g of Sucrose dissolved in 250 ml of water |
|
| Regular Bake beans in tomato sauce | Other | Bake beans in tomato sauce containing 14 g of sugar |
|
| Bake beans in tomato sauce, reduced sugar | Other | Bake beans in tomato sauce containing 12.2 g of sugar |
|
| Bake beans in tomato sauce, low GI | Other | Bake beans in tomato sauce containing 7.2 g of sugar |
|
| ID | Term |
|---|---|
| D003924 | Diabetes Mellitus, Type 2 |
| D009765 | Obesity |
| D011236 | Prediabetic State |
| ID | Term |
|---|---|
| D003920 | Diabetes Mellitus |
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
| D004700 | Endocrine System Diseases |
| D050177 | Overweight |
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D001835 | Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| ID | Term |
|---|---|
| D013395 | Sucrose |
| ID | Term |
|---|---|
| D004187 | Disaccharides |
| D009844 | Oligosaccharides |
| D011134 | Polysaccharides |
| D002241 | Carbohydrates |
| D000073893 | Sugars |
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