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The cardiovascular parameters of prolonged physical exercice have been studied, but very little data is available about the retinal vascularization.
The eye allows in vivo visualization of micro-vascularisation and is considered as an excellent marker of general vascular condition.
The marathon is an intense and prolonged exercise (running 42.195 km) in aerobic environment. Thus the investigators propose to study the vascular parameters of the retina, before and after this physical exercise.
This will allow : 1) to collect information on the physiology of the retinal vascularization to prolonged effort, 2) to detect any retinal damage (haemorrhages, edema, occlusion ...), not known to date.
The results may highlight vascular effects related to retinal hypoxia (venous tortuosity, haemorrhage, venous occlusion, hypoxic edema). Furthermore the results may urge prevention in this sport more and more democratized.
the investigators hypothesized that prolonged physical exercice causes a change in retinal vascularization.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Person running a marathon | Exams performed before (1 month maximum) and after the marathon (1 hour maximum) : Color retinography Optical Coherence Tomography - Angiography (OCT-A) Blood pressure measurement |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Color retinography | Diagnostic Test | Non mydriatic color retinography within 1 month before and within 1 hour after the marathon |
|
| Measure | Description | Time Frame |
|---|---|---|
| Density of retinal vascular plexuses | Percentage, Measurement with OCT-A | up to 1 hour |
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Inclusion Criteria:
Exclusion Criteria:
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Person running a marathon
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| Name | Affiliation | Role |
|---|---|---|
| Martine MAUGET FAYSSE | Fondation A. de Rothschild | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Fondation A de Rothschild | Paris | 75019 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 33824079 | Derived | Mauget-Faysse M, Arej N, Paternoster M, Zuber K, Derrien S, Thevenin S, Alonso AS, Salviat F, Lafolie J, Vasseur V. Retinal and choroidal blood flow variations after an endurance exercise: A real-life pilot study at the Paris Marathon. J Sci Med Sport. 2021 Nov;24(11):1100-1104. doi: 10.1016/j.jsams.2021.03.013. Epub 2021 Mar 30. |
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| ID | Term |
|---|---|
| D001795 | Blood Pressure Determination |
| ID | Term |
|---|---|
| D003935 | Diagnostic Techniques, Cardiovascular |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
| D010808 | Physical Examination |
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| OCT-A | Diagnostic Test | Optical Coherence Tomography - Angiography within 1 month before and within 1 hour after the marathon |
|
| Blood pressure measurement | Diagnostic Test | Blood pressure measurement within 1 month before and within 1 hour after the marathon |
|