Prolonged corrected QT interval (QTc) has been observed in about half of patients with liver cirrhosis. Marked prolongation of QTc (ie, 500 msec) has been considered to be a risk factor for fatal ventricular arrhythmia, such as torsade de pointes,7,8 which has been reported in liver transplantation (LT) surgery. In a previous study, prolonged QTc interval ( 500 msec) was frequently observed throughout the procedure of LT, even among patients with baseline QTc 440 msec. Therefore, it is important to optimize electrolyte balance and hemodynamic status to reduce greater risk of perioperative arrhythmias.

The investigators hypothesized that the change of QTc interval might be differ according to method of general anesthesia (inhalation agent vs. intravenous agent).

Inclusion Criteria:

• patients with liver cirrhosis who will undergo planned liver transplantation

Exclusion Criteria:

• 1. emergent liver transplantation
• 2. unstable angina
• 3. recent MI(Myocardial Infarction)
• 4. uncontrolled hypertension (diastolic BP > 110mmHg)
• 5. implantable cardiac defibrillator
• 6. severe obesity (BMI>30kg/m2)
• 7. allergy to propofol

Data will become available when the script for this study is accepted in journal.

patients will be randomly allocated to 2 groups using computer-generated randomization method. Care provider will not be blinded to the group allocation, because anesthesiologists should be aware of the method of anesthesia.