Response to Clenbuterol in Humans

Detectability of Clenbuterol and Physiological Response in Human Skeletal Muscle

Due to the long half-life (~36 hr) of clenbuterol, detection methods such as dried blood spots (DBS) are a potentially suitable method to easily and non-invasively detect doping misuse of this compound for several days after ingestion. If, and how long, the compound can be detected by DBS has not yet been investigated but is of interest due to its potential in doping-control. The aim is to evaluate whether abuse of clenbuterol can be detected at relevant concentration levels in samples obtained using DBS and to assess the physiological response to clenbuterol in skeletal muscle..

Inclusion Criteria:

• Healthy
• Male
• 18-40 years of age
• No known contraindications for anabolic drugs (e.g. cancer)

Exclusion Criteria:

• Abnormal ECG
• Steroid abuse
• Ongoing use of prescription medication
• heavy resistance training more than 2 times weekly
• Disease deemed by the MD to infer a risk to participate in the trial