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| Name | Class |
|---|---|
| University of Primorska | OTHER |
| Albert Einstein College of Medicine | OTHER |
| Vrije Universiteit Brussel | OTHER |
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Within this project the investigators tested the effectiveness of 2-month of computerized cognitive training (CCT) on CogniFit online platform on 77 older adults, which were randomly divided into intervention and control group. The investigators tested close (battery of cognitive functions) and far transfer (postural and mobility control, EEG, blood samples) of the CCT. Additionally, the investigators were interested into seeing a long-lasting effect, therefore participants were brought back to the laboratory 1 year post CCT.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Intervention group | Experimental | Participants in the intervention group received 24 sessions of computerized cognitive training, with a total time of 960 min. |
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| Active control group | Active Comparator | Participants in the control group attended activities separate activities, such as learning about healthy lifestyle, had cooking and other social lessons for the same amount as the intervention group performed cognitive training. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Computerized cognitive training | Other | Intervention used CogniFit platform with Personalized brain training sub-option |
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| Measure | Description | Time Frame |
|---|---|---|
| Change in gait speed | The primary outcome is change in gait speed during single- and dual-task conditions from baseline to post-intervention. | up to 8 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Executive control (Trail-Making Task Forms A and B) | Secondary outcome is change in executive control, measured with TMT A and B tests | up to 8 weeks |
| Sensorimotor integration measured with EEG/ERP methodology |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Center for Daily Activity Koper (Slovenia) | Koper | 6000 | Slovenia |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 25938245 | Background | Marusic U, Kavcic V, Giordani B, Gerzevic M, Meeusen R, Pisot R. Computerized spatial navigation training during 14 days of bed rest in healthy older adult men: Effect on gait performance. Psychol Aging. 2015 Jun;30(2):334-340. doi: 10.1037/pag0000021. Epub 2015 May 4. | |
| 20643703 | Result | Verghese J, Mahoney J, Ambrose AF, Wang C, Holtzer R. Effect of cognitive remediation on gait in sedentary seniors. J Gerontol A Biol Sci Med Sci. 2010 Dec;65(12):1338-43. doi: 10.1093/gerona/glq127. Epub 2010 Jul 19. |
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| ID | Term |
|---|---|
| D060825 | Cognitive Dysfunction |
| ID | Term |
|---|---|
| D003072 | Cognition Disorders |
| D019965 | Neurocognitive Disorders |
| D001523 | Mental Disorders |
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| ID | Term |
|---|---|
| D000072466 | Cognitive Remediation |
| D000091942 | Cognitive Training |
| ID | Term |
|---|---|
| D001521 | Behavior Therapy |
| D011613 | Psychotherapy |
| D004191 | Behavioral Disciplines and Activities |
| D000066530 | Neurological Rehabilitation |
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Participants in the intervention group followed a computerized cognitive training program for 2-months, 3x/week, 40min/session
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A single-blind randomized controlled trial
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Secondary outcome is change ERP components P1, N1, P2 and P3 (amplitudes and latencies)
| up to 8 weeks |
| Brain-derived neurotrophic factor (BDNF) extracted from peripheral blood sampling | Secondary outcome is change in plasma BDNF plasma extraction evaluated in pg/mL | up to 8 weeks |
| 29680203 | Result | Marusic U, Verghese J, Mahoney JR. Cognitive-Based Interventions to Improve Mobility: A Systematic Review and Meta-analysis. J Am Med Dir Assoc. 2018 Jun;19(6):484-491.e3. doi: 10.1016/j.jamda.2018.02.002. Epub 2018 Apr 19. |
| D012046 | Rehabilitation |
| D000359 | Aftercare |
| D003266 | Continuity of Patient Care |
| D005791 | Patient Care |
| D013812 | Therapeutics |
| D006296 | Health Services |
| D005159 | Health Care Facilities Workforce and Services |