Prospective Multicenter Nationwide Registry of Children With Eosinophilic Esophagitis

Prospective Multicenter Nationwide Registry of Children With Eosinophilic Esophagitis

1. Registry of demographic, clinical, endoscopic and histological data at baseline.

2. Registry of patients treated with PPI:

   • Clinical, endoscopic and histological response at 8-12 weeks of induction treatment
   • Clinical, endoscopic and histological response at 6 and 12 months weeks of maintenance treatment

3. Registry of patients treated with two foods elimination diet:

   • Clinical, endoscopic and histological response at 8-12 weeks of induction treatment
   • Identification of food trigger: milk, gluten or milk and gluten
   • Clinical, endoscopic and histological response at one year elimination of food trigger
   • Registry of adverse events

4. Registry of patients treated with swallowed steroids (budesonide or fluticasone):

   • Clinical, endoscopic and histological response at 8-12 weeks of induction treatment
   • Clinical, endoscopic and histological response at 6 months of maintenance steroid treatment
   • Registry of adverse events

Inclusion Criteria:

• Children from 1 month to 18 years with a new diagnosis of eosinophilic esophagitis (EoE) according to the recent European guidelines (symptoms of esophageal dysfunction + eosinophilic infiltrate of the esophagus > 15 eos / CGA)
• And that they need to start treatment with any of the following options: PPI, diet excluding cow's milk and gluten, or swallowed corticosteroids .

Exclusion Criteria:

• Presence of pathological eosinophilia at the gastric or duodenal level (eosinophilic gastroenteritis)
• Simultaneous treatment with more than one treatment modality (PPI, empirical elimination diet, swallowed corticosteroids).