The main objectives of this study are to assess the safety, tolerability, pharmacokinetics (PK), and food effect of BLU-782 in healthy adult subjects.

Inclusion Criteria:

• Medically healthy
• Non-smoker
• Body mass index (BMI) ≥ 18 and ≤ 32 kg/m2
• No clinically significant cardiac history
• No current electrocardiogram (ECG) abnormality
• Female must not be of childbearing potential

Exclusion Criteria:

• History of or current mental or legal incapacitation or major emotional problems
• History or current clinically significant medical/psychiatric condition/disease
• History of any illness that, in the opinion of the Investigator, might impact the results of the study or pose an additional risk to the participant
• History or current alcoholism/drug abuse
• History or current allergy to the study drug or a similar drug