Continuous Glucose Monitoring to Aid Weight Loss in Prediabetes

Real-Time Continuous Glucose Monitoring to Aid Weight Loss in Prediabetes

The primary objective of this study is to determine whether intermittent use of continuous glucose monitor will facilitate weight loss in individuals who are overweight/obese with prediabetes.

Continuous glucose monitoring (CGM) has revolutionized the treatment of patients on intensive insulin therapy and its utility can also be harnessed to help individuals with prediabetes make healthful lifestyle changes. Successful weight loss requires adherence to lower calories, regular exercise, and self-monitoring. This proposal will test the hypothesis that intermittent CGM will facilitate all of these components for successful weight loss by functioning as a continuous self-monitor and guiding healthful food choices and physical activity.

Inclusion Criteria:

• Overweight/obese (BMI 25-40 kg/m2)
• Prediabetes (fasting glucose 100-125 mg/dL and/or HbA1c 5.7-6.4%)

Exclusion Criteria:

• On glucose-lowering medications (e.g., metformin)
• On weight-loss medications