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The performance of STIs and clinical scores alone and their combination to predict short term prognosis of acute decompensated heart failure.
Acute heart failure is a leading cause of hospitalization and death.Prediction of these adverse events is still challenging.
STI is an old technique based on the recording of two parameters: electrocardiogram and phonocardiogram, and from them measuring the different systolic intervals:
pre-ejection period (PEP),electro-mechanic activation time (EMAT), Left ventricular ejection time (LVET) and systolic time ratio (RTS) were measured.
The aim of these study is to demonstrate whether systolic time intervals (STIs) can improve clinical scores EFFECT (Enhanced Feedback for Effective Cardiac Treatment) and GWTG-HF (Get With the Guidelines-Heart Failure) for predicting 30 day mortality and readmission in patients with acute decompensated heart failure (ADHF) in the ED.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| AHF/HFpEF | AHF with preserved ejection fraction Acoustic cardiography was performed for all participants using the BIOPAC Prognostic scores were calculated for every patient |
| |
| AHF/HFrEF | AHF with reduced ejection fraction Acoustic cardiography was performed for all participants using the BIOPAC Prognostic scores were calculated for every patient |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| biopac | Device | Acoustic cardiography was performed for all participants using the BIOPAC system with "Student Lab" software version 3.7.2. An electrocardiogram was obtained by two electrodes placed at the right upper limb and the lower left limb. Simultaneously heart sounds were recorded with a specific sensor placed at the mitral focus. |
| Measure | Description | Time Frame |
|---|---|---|
| compare the STIs prognostic performance against clinical scores | the area under ROC curve of the Systolic Time Intervals compared to the one of the EFFECT and GWTG HF scores | 30 days |
| Measure | Description | Time Frame |
|---|---|---|
| compare the STI prognostic performance between HFpEF and HFrEF patients | compare the STI prognostic performance between HFpEF and HFrEF patients using the area under curve estimation of the ROC curve of the three systolic time intervals (PEP;EMAT measured in milliseconds,and PEP/EMAT) of the two groups | 30 days |
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Inclusion Criteria:
Exclusion Criteria:
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all patients aged more than 18 years admitted to the ED with the diagnosis of acute decompensated heart failure
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| Name | Affiliation | Role |
|---|---|---|
| Nouira Semir, Pr | University hospital of Monastir | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Emergency department of university hospital Fattouma Bourguiba of Monastir Monastir, Monastir Tunisia | Monastir | 5000 | Tunisia |
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| Label | URL |
|---|---|
| official department website | View source |
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| ID | Term |
|---|---|
| D004417 | Dyspnea |
| D006333 | Heart Failure |
| ID | Term |
|---|---|
| D012120 | Respiration Disorders |
| D012140 | Respiratory Tract Diseases |
| D012818 | Signs and Symptoms, Respiratory |
| D012816 | Signs and Symptoms |
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|
| prognostic scores | Diagnostic Test | Effect and GWTGHF were calculated for every patient |
|
| D013568 | Pathological Conditions, Signs and Symptoms |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |