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Acute kidney injury (AKI) is the most common complication in patients after cardiac surgery. An usual estimation of risk for AKI is estimation of serum creatinine, which is unreliable indicator of AKI risk. Because of that, today different biomarkers are investigated to predict incidence for development AKI after cardiac surgery. This investigation will try to find potentially risk patients for developing AKI after cardiac surgery by using conventional markers (creatinine, glomerular filtration rate) in perioperative period comparing with two different biomarkers neutrophil gelatinase-associated lipocalin (NGAL) and growth differentiation factor 15 (GDF-15) which are proven markers in patients with increased risk for AKI development.
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| Measure | Description | Time Frame |
|---|---|---|
| Consecutive values of neutrophil gelatinase-associated lipocalin (NGAL) | By the changing of NGAL values in consecutive measuring, predict which patients are in increased risk for development of AKI | One year |
| Consecutive values of growth differentiation factor 15 (GDF-15) | By the changing of GDF-15 values in consecutive measuring, predict which patients are in increased risk for development of AKI | One year |
| Consecutive values of glomerular filtration rate (GFR) | By the changing of GFR values in consecutive measuring, predict which patients are in increased risk for development of AKI | One Year |
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Inclusion Criteria:
Exclusion Criteria:
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Patients scheduled for cardiac surgery with usage of cardiopulmonary bypass
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Nikola Bradic, MD | Contact | +385 91 589 3480 | nbradic@kbd.hr |
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| ID | Term |
|---|---|
| D058186 | Acute Kidney Injury |
| ID | Term |
|---|---|
| D051437 | Renal Insufficiency |
| D007674 | Kidney Diseases |
| D014570 | Urologic Diseases |
| D052776 | Female Urogenital Diseases |
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| D005261 |
| Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D052801 | Male Urogenital Diseases |