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Anemia is the commonest hematological disorder that occurs in pregnancy. According to the recent standard laid down by 'WHO', anemia is present when the Hemoglobin (Hb) concentration in the peripheral blood is 11 gm/dl or less. The most common cause of anemia in pregnancy is lack of iron. This study is done to compare the efficacy and tolerability of iron amino acid chelate and that of iron salts (ferrous fumarat).
Anemia is the commonest hematological disorder that occurs in pregnancy. According to the recent standard laid down by 'WHO', anemia is present when the Hemoglobin (Hb) concentration in the peripheral blood is 11 gm/dl or less. The most common cause of anemia in pregnancy is lack of iron. This study is done to compare the efficacy and tolerability of iron amino acid chelate and that of iron salts (ferrous fumarat).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Amino Acid chelated iron tab 15 mg group | Experimental | Contain 75 pregnant women will recommended to take ferrotrone(iron chelated amino acid containing 15mg elemental iron) prepared by egyptian pharmaceutical company (nerhadou) once daily (a dose recommended by the company of the product). |
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| Ferrous Fumarate tab 350 mg( 115 mg elemental iron) group | Active Comparator | Contain 75 pregnant women will recommended to take ferrous fumarate e.g. Hema-caps (ferrous fumarate 350 mg with elemental iron 115mg) prepared by another egyptian pharmaceutical company (Amoun pharmaceutical company) once daily but in sever cases of iron deficiency anemia (Hb<9g/dl) this dose can be doubled as recommended by the company of the product. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Amino Acid chelated iron tab 15 mg | Drug | Contain 75 pregnant women will recommended to take ferrotrone(iron chelated amino acid containing 15mg elemental iron) a dose recommended by the company of the product. Iron tablets should be taken at night or at least 1 hour prior to food to maximise absorption. Substances that inhibit absorption such as tannins & milk should be avoided but fruit juice contain ascorbic acid taken in conjunction with iron supplements increases their absorption. Follow up will be done for all the pregnant women included in our studies at baseline & then 4, 8 & 12 weeks after treatment at each visit breif history for outcomes and adverse effects will reviewed. |
| Measure | Description | Time Frame |
|---|---|---|
| Hemoglobine (Hb) Rise | follow up CBC after 12 weeks of treatment given | after 12 weeks of treatment. |
| Measure | Description | Time Frame |
|---|---|---|
| Hemoglobine (Hb) Rise | Follow up CBC after 4,8 weeks of treatment given | after 4,8 weeks of treatment. |
| Adverse effects of the medication given | constipation, nausea, allergy. |
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Inclusion Criteria:
Exclusion Criteria:
this trial conducted on treatment of iron deficiency anemia in pregnant women
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Ahmed Elshahawy, MD | Contact | +01223266380 | ahmedshafy@hotmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Ahmed Elshahawy, MD | Ain Shams University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Ain shams university maternity hospital | Recruiting | Cairo | 25187 | Egypt |
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| Ferrous Fumarate tab 350 mg( 115 mg elemental iron) | Drug | 75 pregnant women will recommended to take ferrous fumarate e.g. Hema-caps (ferrous fumarate 350 mg with elemental iron 115mg) prepared by another egyptian pharmaceutical company (Amoun pharmaceutical company) once daily but in sever cases of iron deficiency anemia (Hb<9g/dl) this dose can be doubled as recommended by the company of the product. Some instructions will be given to all the pregnant women included in our study as follow: Iron tablets should be taken at night or at least 1 hour prior to food to maximise absorption. Substances that inhibit absorption such as tannins & milk should be avoided but fruit juice contain ascorbic acid taken in conjunction with iron supplements increases their absorption. Follow up will be done for all the pregnant women included in our studies at baseline & then 4, 8 & 12 weeks after treatment at each visit breif history for outcomes and adverse effects will reviewed. |
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| 3months |
| ID | Term |
|---|---|
| D018798 | Anemia, Iron-Deficiency |
| ID | Term |
|---|---|
| D000747 | Anemia, Hypochromic |
| D000740 | Anemia |
| D006402 | Hematologic Diseases |
| D006425 | Hemic and Lymphatic Diseases |
| D000090463 | Iron Deficiencies |
| D019189 | Iron Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
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| ID | Term |
|---|---|
| C031621 | ferrous fumarate |
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