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This study aims to study the digestibility of isolated duckweed protein. The digestibility of the isolated duckweed protein will be compared to an isolated benchmark protein whey.
Objective: The primary objective is to investigate the digestibility of isolated duckweed protein and the isolated benchmark protein whey.
Study design: The study is a cross-over, double blind, controlled trial in which study participants will visit the research facility on two occasions under fasting conditions. Subjects will receive two protein sources in randomized order with a washout period of one week. Blood will be collected via a catheter before and up-to 3 hours after protein consumption.
Study population: We aim to include 12 healthy volunteers aged 18-50 years. Intervention: Study participants will receive 20 grams of isolated duckweed protein and the isolated benchmark protein whey.
Main study parameters/endpoints: The main study parameter is blood amino acids measured before and after consumption of 20 g protein.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Duckweed protein | Experimental | 20 gram of isolated protein |
|
| Whey protein | Experimental | 20 gram of isolated protein |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Duckweed protein | Dietary Supplement | 20 grams isolated protein |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Change in blood free amino acids (e.g. Degree of digestibility) | postprandial test, determine free amino acids in blood samples collected before and after a postprandial challenge test | 20 gram protein will be consumed and blood samples will be taken before and up to 3 hours after protein consumption |
| Measure | Description | Time Frame |
|---|---|---|
| change in plasma insulin | before and after a postprandial challenge test | 20 gram protein will be consumed and blood samples will be taken before and up to 3 hours after protein consumption |
| change in plasma glucose |
| Measure | Description | Time Frame |
|---|---|---|
| change in visual analogue scale (VAS) scores on intestinal complains | On a scale ranging from worst-best outcome (higher scores are better) | daily from day1 until day3 after the intervention |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Diederik Esser, PhD | Wageningen Research | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Stichting Wageningen Research | Wageningen | Gelderland | 6708 WG | Netherlands |
will not be shared
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| ID | Term |
|---|---|
| D000067816 | Whey Proteins |
| ID | Term |
|---|---|
| D008894 | Milk Proteins |
| D000080224 | Animal Proteins, Dietary |
| D004044 | Dietary Proteins |
| D011506 | Proteins |
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| Whey protein |
| Dietary Supplement |
20 grams isolated protein |
|
before and after a postprandial challenge test
| 20 gram protein will be consumed and blood samples will be taken before and up to 3 hours after protein consumption |
| D000602 |
| Amino Acids, Peptides, and Proteins |
| D000067796 | Whey |
| D008892 | Milk |
| D003611 | Dairy Products |
| D005502 | Food |
| D000066888 | Diet, Food, and Nutrition |
| D010829 | Physiological Phenomena |
| D019602 | Food and Beverages |