Evaluation of Kidney Graft's Fibrosis With Real Time Shear-wave Elastography
Evaluation of Kidney Graft's Fibrosis With Real Time Shear-wave Elastography
Kidney graft's fibrosis is correlated with prognostic of kidney's graft, wathever the initial etiology. Actually, that evaluation is based on histologic score of Banff FI/AT (0 to III). It is obtained thanks to punction-biopsy, which is invasive and can lead complications. This exam is systematic on M3 of the transplantation.
Tissue's fibrosis is a proliferation of extracellular matrix, leading to an increase of fibrosed tissue rigidity.
Elastography is an ultrasound technique allowing evaluation of tissues' rigidity.
The purpose is the validation of elastograhpy, innovative and non -invasive technique, and more specifically Shear Wave Elastography (SWE). For this, strain ratio (SR) could improve intra-operator variability and estimate fibrosis' degree of kidney's graft.
Kidney graft's fibrosis is correlated with prognostic of kidney's graft, wathever the initial etiology. Actually, that evaluation is based on histologic score of Banff FI/AT (0 to III). It is obtained thanks to punction-biopsy, which is invasive and can lead complications. This exam is systematic on M3 of the transplantation.
Tissue's fibrosis is a proliferation of extracellular matrix, leading to an increase of fibrosed tissue rigidity.
Elastography is an ultrasound technique allowing evaluation of tissues' rigidity.
The purpose is the validation of elastograhpy, innovative and non -invasive technique, and more specifically Shear Wave Elastography (SWE). For this, strain ratio (SR) could improve intra-operator variability and estimate fibrosis' degree of kidney's graft.
Inclusion Criteria:
Exclusion Criteria:
Dual kidney graft
Hydronephrosis / urinary obstacle
Pathologies with an intrinsic compression on the graft
Stenosis hemodynamically significant of graft artery (lengthening of Systolic Ascent Time > 70 ms)
Contra-indication to systematical punction-biopsy on Month 3 :
Opposition to use the data