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| Name | Class |
|---|---|
| Revalidatie & MS Centrum Overpelt | OTHER |
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Multiple Sclerosis (MS) patients with subjective dysphagia will be tested for tongue strength fatigue using a strictly defined fatigue paradigm. A maximum of 40 sets will be performed, each set consisting of 5 repetitions of 80% of maximum isometric pressure (MIP) at the anterior tongue, followed by a MIP at the anterior tongue. Cut-off criteria are a MIP <50% of the baseline MIP, pronounced subjective discomfort and/or exceeding the allocated test time of 30 minutes.
Eligibility is Mini-Mental State Exam-score (MMSE) > 23, a Eating Assessment Tool-score (EAT-10) > 3, or a Functional Oral Intake Scale-score (FOIS) < 7, or failing the Yale Swallow Protocol.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Iowa Oral Performance Instrument (IOPI) | Experimental | All MS patients will be included in this arm to compare with a historical control arm. Iowa Oral Performance Instrument (IOPI). |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Iowa Oral Performance Instrument (IOPI) | Device | Using biofeedback to attain repetitions of 80% of baseline MIP. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Number of successful repetitions | The number of repetitions where the target force was developed. | 30 minutes |
| Evolution of MIP during subsequent repetitions | The change in MIP after each 5 repetitions. | 30 minutes |
| Measure | Description | Time Frame |
|---|---|---|
| Baseline MIP as predictor for number of repetitions | Does baseline MIP predict the number of successful repetitions. | 30 minutes |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Jan Vanderwegen, MD | Contact | 03 241 08 29 | jan.vanderwegen@thomasmore.be |
| Name | Affiliation | Role |
|---|---|---|
| Jan Vanderwegen | Thomas More University College | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Thomas More University College of Applied Sciences | Antwerp | Antwerpen | 2018 | Belgium |
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| ID | Term |
|---|---|
| D018908 | Muscle Weakness |
| D005221 | Fatigue |
| D009103 | Multiple Sclerosis |
| D003680 | Deglutition Disorders |
| ID | Term |
|---|---|
| D009135 | Muscular Diseases |
| D009140 | Musculoskeletal Diseases |
| D020879 | Neuromuscular Manifestations |
| D009461 | Neurologic Manifestations |
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| D009422 | Nervous System Diseases |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D012816 | Signs and Symptoms |
| D020278 | Demyelinating Autoimmune Diseases, CNS |
| D020274 | Autoimmune Diseases of the Nervous System |
| D003711 | Demyelinating Diseases |
| D001327 | Autoimmune Diseases |
| D007154 | Immune System Diseases |
| D004935 | Esophageal Diseases |
| D005767 | Gastrointestinal Diseases |
| D004066 | Digestive System Diseases |
| D010608 | Pharyngeal Diseases |
| D010038 | Otorhinolaryngologic Diseases |