In this single-center study the investigators will analyze gender differences among patients with suspected sepsis admitted to the Emergency Department at Södersjukhuset during a period of two years. About 11 000 patients will be included. Patient data including fluid therapy will be drawn from the electronic medical record; Take Care and Clinisoft. In the logistic regression analysis, the investigators will adjust for age, gender, comorbidities, vital signs, preliminary focus of infection, level of care and renal replacement therapy. The aim is to analyze gender differences in fluid treatment and the response to fluid treatment and if the treatment is associated with differences in mortality.

Inclusion Criteria:

• Patients admitted to the emergency department with suspected sepsis (defined by blood culture taken and intravenous sepsis-antibiotics prescribed within 48 hours) and fulfilling sepsis-3 definition of sepsis (sequential organ failure assesment score of 2 or more)

Exclusion Criteria:

• Patients transferred from other hospitals or treatment clinics.

The population is patients admitted at the emergency department at Södersjukhuset in Southern Stockholm. Södersjukhuset has 600 hospital beds and manages most medical fields except for highly specialized care for example neuro and thoracic surgery. 130 000 patients are seeking medical care yearly which makes the emergency department at Södersjukhuset the most frequented in Scandinavia.