Optical Coherence Tomography Guided Percutaneous Coronary Intervention for Drug-eluting In-stent Restenosis

Optical Coherence Tomography Guided Percutaneous Coronary Intervention for Drug-eluting In-stent Restenosis: A Prospective Registry Trial

This study is a prospective, registry trial aimed to compare the clinical and angiographic outcomes of OCT-guided and angiography-guided PCI in patients with coronary DES-ISR.

Inclusion Criteria:

• Age 18 years or older
• Patients with angina or evidence of myocardial ischaemia
• Patients with restenotic lesions in a previously DES area of a coronary artery
• Patients suitable to receive any types of percutaneous coronary intervention (including balloon angioplasty and stent implantation)
• The stent diameter of DES-ISR is 2.5mm to 4.0mm
• Target lesion length < 30mm
• Target lesion stenosis ≥ 70% diameter stenosis on visual assessment, or ≥ 50% diameter stenosis and with evidence of myocardial ischaemia ischemic

Exclusion Criteria:

• Patients with acute myocardial infarction with 1 week
• Patients with evidence of extensive thrombosis in the target vessel
• Patients with left main coronary artery disease
• Patients with cardiogenic shock, left ventricular ejection fraction < 40%,significant renal dysfunction and severe heart valve disease
• Patients who had cerebral stroke within 6 months before PCI
• Patients with a life expectancy < 1 year
• Patients not able to adhere to follow-up visits